Chromium picolinate side effects series#
Chromium picolinate side effects free#

Chromium boosts insulin action, thus increasing the insulin-signaling pathway, reverses regulators that stunt insulin sensitivity, and increases glucose uptake (10). One of the best-studied effects of chromium is its effects on insulin action. Help to regulate insulin action, glucose intolerance, and reduce diabetes symptoms.

Some of the most stand-out benefits are detailed below.

There are several health benefits linked to chromium picolinate supplementation. However, it is always important to follow the dosage recommendations and consult with your doctor before taking on a new supplement regimen.

Chromium picolinate side effects free#

Some studies have suggested that chromium has the potential to generate free radicals in the body, but chromium picolinate is metabolized so quickly (about 1 day) that it minimizes any potentially negative effects over-supplementation may have ( 16, 17, 18).Įvidence shows that the type of chromium used in nutritional supplements (chromium picolinate) is safe at recommended doses, and is most likely safe at higher doses. However, it is important to note that different forms of chromium are metabolized differently, and thus have different effects on human health ( 9, 19).Ĭases of toxicity with chromium found in supplements are most commonly caused by exceeding the recommended daily doses by 3-18 times ( 13, 14).Įven so, lab studies have shown that even at several thousand times the upper limit of consumption, supplementation with trivalent Cr is considered safe and adequate ( 15). Studies show that chromium picolinate is safe to consume at recommended doses, and is, indeed, necessary for human health ( 1, 11, 12).Ĭhromium has been scrutinized after studies demonstrated that certain forms of the mineral have toxic effects on humans. In short, trivalent forms of chromium may improve the use of glucose in the blood for energy while it also helps prevent the body from breaking down proteins, like the ones found in your muscles, for energy. While it enhances insulin signaling, chromium picolinate may also inhibit the breakdown of proteins ( 8).

Chromium picolinate side effects series#

Many biochemicals models have set out to propose the mechanism of action of chromium in the body.Ĭhromium is found in such low quantities in the blood, is often studied while individuals are on other medications, and may change its effect based on individual genetics, that studies show that it is difficult to pinpoint exactly how it works ( 4, 5).ĭespite difficulties in understanding how it works in the body, regarding its role in carbohydrate and lipid metabolism, recent studies show that chromodulin, a peptide (protein building block) can saturate itself with chromium and bind to insulin receptors and amplify insulin signaling ( 6).Ī series of other biochemical reactions occur, eventually signaling an increase of glucose uptake and storage ( 7).

Normal brain function and other processes in the body.

Aids in insulin action and the breakdown of glucose.

the breakdown of fats and carbohydrates.