#SYMPHYTUM OFF SKIN#

Information is shared for educational purposes only, and is believed to be accurate at the time it was developed, but it should be viewed as general information, which may need to be adjusted to fit individual circumstances.

We do not aim to diagnose, treat, cure, or prevent any illness or disease. The content of this website is for informational purposes only. Social media links are at the top and bottom of the page.Ĭopyright 1999 by Sharol Tilgner, N.D. Remember To Send This To Friends And Family Who Will Benefit From Reading It! If you are looking for directions on making teas or tinctures, please see our 'Making Herbal Products' page. If so, someone with an active phase I biotransformation system and a slow phase II biotransformation would be more likely to show toxicity. Evidence from the literature suggests that bioactivation of pyrrolizidine alkaloids by cytochrome P450 enzymes is required for their toxicity. There was a slight increase in weight of the rats. In a 2016 experiment where scientists looked for veno-occlusive disease, rats were given 250 mg/kg of Symphytum root with a 0.375 mg/kg pyrrolizidine content on a daily basis for 28 days and they found no histopathological damage to the liver. The FDA warns people not to use this plant internally or even externally on open wounds or on mucous membranes due to the pyrrolizidine content. It is also contraindicated in pregnancy and nursing mothers. Pyrrolizidines are potentially hepatotoxic, pneumotoxic, genotoxic and carcinogenic. Pyrrolizidine poisoning is known to cause veno-occlusive disease.

#SYMPHYTUM OFF SKIN#

But internal use is no longer advised due to the possibility of pyrrolizidine alkaloid poisoning inducing veno-hepato-occlusive disease.Įxternally it decreases the healing time for skin wounds and irritations and has been shown to act as a mild analgesic.Ĭontraindications: Do not use internally unless using a product with low/no pyrrolizidines listed on the label. Comfrey can also be used as a gargle in periodontitis and pharyngitis. It has been used for arthritis, dislocations, contusions, hematomas, thrombophlebitis, phlebitis, parotitis, and glandular swellings. It acts as an anti-inflammatory when there is damage to the periosteum, promotes callus formation in fractures and decreases inflammation of tendon sheaths. Use: Externally: (a) Contusions, (b) Sprains, (c) Dislocations, (e) Wounds, (f) Burns, (g) Ulcers, (h) All inflammatory skin disorders.Ĭomfrey's demulcent and anti-inflammatory effects have been used historically as an internal agent for soothing mucous membrane irritation in the gastrointestinal tract, respiratory tract and urinary tract. Taste/Smell: Mucilaginous, nutritious tasting, bland.ĭosage: Used externally as a poultice, paste, or fomentation. Parts used: Root and main rib of leaf have the most mucilage and allantoin. Comfrey - Symphytum officinalis in the Boraginaceae or Borage family